Make a Donation
Support the pets & people of Southeast Missouri with one simple gift.
Dontate Online
Your Donation Makes a Real Difference
Every dollar you give helps feed, heal, and house animals right here in Cape Girardeau and the surrounding communities. As a nonprofit, we rely entirely on local support to provide medical care, adoption services, education programs, and emergency shelter for hundreds of pets each year.

Whether it’s a one-time gift or a monthly donation, your support gives animals a second chance—and helps families across Southeast Missouri.
Ways to Give
Monthly Giving
Set up a recurring gift to provide steady support all year long. Even small amounts make a big impact over time.
Mail a Check
Prefer to give by mail? Send a check to:
180 Weston Street, Cape Girardeau, Missouri 63701, United States
Online Donations
Click the secure link below to make a one-time or recurring donation. It’s fast, safe & goes straight to work for the animals.
Wish List & Supplies
We also accept donations of pet food, blankets, cleaning supplies, and other daily essentials.
Tribute Gifts
Honor a loved one—human or pet—with a donation in their name. Perfect for birthdays, memorials, or just because.
Your Impact
- Covers life-saving medical treatment
- Funds spay & neuter surgeries through SNAP
- Supports humane education for local kids
- Helps rescue, shelter & rehome animals in need
- Keeps our facility running year-round
No gift is too small to matter. Every bit helps us care for more animals and do more good.
The Humane Society of Southeast Missouri DBA Southeast Missouri Pets is a 501(c)(3) non-profit organization that does not receive any funding from state/federal agencies and is not operated by any fellow SPCAs. Our support comes from individuals who share our passion for saving pets.
All donations made to the Southeast Missouri Pets are tax-deductible to the extent allowed by law.
Our tax ID number is 43-1108057.
Frequently Asked Questions About Donating
Ready to Make a Difference?
Use our secure link to donate today and help us give animals the care, safety & love they deserve.
Is my donation tax-deductible?
Yes. We are a registered 501(c)(3) nonprofit organization. Your donation is tax-deductible to the extent allowed by law. We recommend keeping your email or mailed receipt for your records.
How do I know my donation is being used responsibly?
We’re a locally run nonprofit and every donation goes directly toward the care, shelter, and medical needs of the animals. We don’t receive government funding, so we’re committed to transparency and stewardship. You’re always welcome to contact us with questions about how funds are used.
What if I want to donate to a specific program or in a specific way?
You can! If you want your gift to support something specific—like the SNAP spay/neuter program, cremation support, or education efforts—just let us know when you donate. We’ll do our best to honor your request.
Do you accept workplace or employer-matched donations?
Yes! Many companies offer matching gift programs or community giving initiatives. Ask your HR department if your donation can be matched—it’s a simple way to double your impact.
Can I organize a fundraiser or supply drive for you?
Absolutely. Whether you're a student, business owner, scout troop, or just an animal lover, we welcome community fundraisers and donation drives. Contact us and we’ll help you get started.
What if I want to stay anonymous?
That’s totally fine. Just let us know on your donation form or when you mail your gift, and we’ll make sure your donation stays private.
Do you need help during the holidays or emergencies?
Yes. Times like summer heat, winter storms, and the holidays are when shelters often need the most help. Donations during these times go a long way in keeping animals safe, warm, and fed.